By invitation · Napa Valley · April 14–15, 2027
Half-Life:100The Future of Employeebuilt on Precision Biology.
Benefits Leadership Conversation
Format
Leadership Panels
Location
Silverado Resort,
Napa
Dates
April 14–15
Seats
24, by invitation · 2027 cohort
The format
Private strategy calibration for senior benefits leaders.
The summit is built around working panels, not passive keynotes. Each session seats four peers on stage for roughly forty-five minutes of structured conversation, so every attendee contributes. Benefits leaders, clinicians, scientists and AI thinkers sit together — the mix is intentional, because better benefits decisions come from hearing how cost, care and biology actually intersect.
- 24
- seats total
- 6
- panels
- 45
- minutes each
Who attends
A closed cohort model for senior leaders in healthcare benefits.
Twenty-four seats, held by people with the authority to act on what is said. The room is curated so that the science, the medicine, the budget and the advice are all represented at the same table.
Benefits leaders — 13 seats
CHROs, VPs of Total Rewards and Heads of Benefits at large self-insured employers. The single largest voice in the room, because the day is built around decisions they are authorized to make.
Consultants & advisors — 8 seats
Senior partners and clinical practice leaders from the national benefits consultancies. They bring the market view and help translate what is discussed into client action.
Physicians — 2 seats
Chief Medical Officers, medical directors and practising clinical leads in metabolic, GI and cardiometabolic care. They keep the biology honest.
Scientists — 1 seat
Principal investigators, research directors and heads of computational, microbiome and metabolic science. One seat to keep the science present without turning the room into a lab meeting.
Eligibility
Attendees are the top operational leader for health benefits or total rewards at a company managing at least 10,000 US employees or 15,000 globally. Scientists, physicians and senior consultants may attend by nomination. No press, no analysts, no vendors.
Agenda
One full day, six panels, one table.
Six working panels across the day, roughly forty-five minutes each, bookended by an opening and a closing keynote.
8:30 AM – 12:30 PM
Arrival, welcome, opening keynote & morning panels
Check-in and coffee, then the opening keynote followed by the morning panels. One 15-minute break.
12:30 – 1:30 PM
Lunch
Seated lunch at the resort — unstructured time with the room.
1:30 – 5:00 PM
Afternoon panels
The remainder of the panels, with one 15-minute break.
5:00 PM
Closing keynote
The day's final session, closing the thread the panels opened.
6:00 PM
Transport to dinner venue
Coaches depart from the resort entrance.
6:30 PM
Cocktails, dinner & entertainment
Hosted dinner at an off-site winery. Partners welcome.
Panel themes
Working topics, shaped with the people on stage.
Every panel is scoped in a pre-event working session with its four participants, so no one arrives cold.
Why Metabolic & Inflammatory Claims Are More Connected Than You Think
Most employers buy point solutions for each condition. The biology says the same pathways drive both.
10 Questions to Ask When Evaluating Solutions in the GLP-1 Space
Coverage, adherence, discontinuation and what happens after the first script — a buyer's checklist.
Assumptions We Have Been Wrong About in the Metabolic Space
Calories-in, calories-out was never the whole story. What else have we misread?
The Real Role of Biology in Care
Genetics, microbiome and metabolic signal as inputs to a care plan, not as a wellness add-on.
Differentiating Capability vs. Sales Talk
How to separate platforms that change outcomes from platforms that change slide decks.
What Solutions Are Worth Buying in a World with ChatGPT Care?
AI is lowering the cost of advice. What does that mean for what employers actually pay for?
Venue & hospitality
Silverado Resort, Atlas Peak Road.
Golf, spa and quiet meeting space in the middle of Napa. The second evening moves off-site to a winery dinner with live music — partners are welcome at no charge.
- —Both dinners are hosted off-site at a winery.
- —Attendees arrange their own flights and room (~$300/night).
- —Room block held at the resort for confirmed guests.
Request an Invite.
Seats are limited to twenty-four and allocated to keep the panel mix balanced. Tell us who you are and we will follow up with dates and the room block.
What it is
A private peer forum, not a stage.
Half-Life:100 is different because Digbi is different.
Half-Life:100 is a closed cohort of senior leaders who run health benefits, clinical programs and benefits advice. No analysts, no press, no posturing. The format is designed so people speak candidly about what they are actually buying, what is working and what is not.
It is not a conference, a mastermind or a vendor forum. There are no paid speaking slots, no monetized introductions and no commercial agenda. The only relationship being built is between peers.
Digbi's contribution is clinical depth: a disease database and care delivery model built on genetics, the gut microbiome and metabolic signal — not a testing report or a longevity score.
Styled text treatment standing in for the final logo asset. Not final art.
We're solving for Employee Health & Benefits, when we treat and manage Chronic Illnesses through Precision Biology.
The approach
Predict, personalize, participate.
Three moves define how precision biology works in practice — and they are the same three a benefits leader can be held to.
Predict
Genetics, the gut microbiome and metabolic signal read together, so risk is visible years before a claim is.
Personalize
Care built for one person's biology — nutrition, therapy and medication matched to what their body actually responds to.
Participate
People stay because the plan fits their life. Participation is the outcome of precision, not a nudge campaign.
Root cause vs. symptoms
Most of healthcare treats the readout, not the biology.
Labs and biomarkers are downstream signals. They tell you something has already gone wrong; they rarely tell you why. Precision biology works one level up — at the genetic, microbial and metabolic drivers that produce those numbers in the first place.
The second point matters just as much: real prevention should not carry a luxury price tag. If root-cause care only reaches executives and concierge members, it is a perk. Delivered through the benefits plan, it becomes healthcare.
- —Upstream biology over downstream metrics.
- —Prevention priced for the whole population, not the top of it.
- —Outcomes a CFO and a clinician can both read.
The newsletter
Where longevity actually gets discussed.
Precision biology is what we do. Half-Life:100 is where we think out loud about what a longer, better life actually looks like. Digbi's company page and Ranjan's own feed stay on precision biology, ROI and case studies. Longevity lives here.
- Weekly
- cadence
- Ranjan Sinha
- author
- Free
- to read
Read by benefits leaders, clinical and scientific partners, investors and partnership contacts. It is a place to think, not a place to be sold to.
Latest issue
First issue comingWhy the decay curve starts earlier than anyone tells you.
The first issue under the Half-Life:100 name. Until it publishes, the back catalogue lives on LinkedIn, where the newsletter began.
Distribution not finalised. This page is being set up as the primary home for the newsletter, with LinkedIn as the second door.
Post visuals
Ready-made LinkedIn posts — same voice as the newsletter, kept off the book's palette.
LinkedIn visuals
Posts from the summit.
Full post mockups — copy, hashtags and a 1080×1080 image — ready to share from the event.
Ranjan Sinha
Half-Life:100 · Newsletter · 1w
The decay curve starts earlier than anyone tells you. Most benefits budgets meet it a decade late.
#Longevity #PrecisionBiology
Ranjan Sinha
Half-Life:100 · Newsletter · 1w
Your biology is not your fate. It is a set of instructions you can edit — and coverage design decides who gets to.
#Healthspan #Benefits
Ranjan Sinha
Half-Life:100 · Newsletter · 1w
100 is the half-life. The rest is a measurement, care and coverage problem.
#Microbiome #Metabolic
From the archive
What the newsletter has been arguing.
A sample of recent issues, written by Ranjan Sinha and read by benefits leaders, clinicians and investors. Every one of them starts at biology and works forward to the buying decision.
- 01Virtual GI care
The future of GI care: why biology, profitability and "in-between" care are the real north stars
What buyers actually get wrong when they read a market report and shop for a GI vendor: the model matters less than the biology underneath it.
- 02Gut microbiome
Microbial guardians of longevity: the gut microbiome as nature's antidote to everyday toxins
The microbiome as a detox organ. What a modern chemical load does to it, and what that costs over a lifetime.
- 03Genetics
Longevity in your DNA: the six genes that shape your lifespan
Six well-studied variants, what each one actually predicts, and why a genotype is a starting point rather than a verdict.
- 04Behaviour
Behaviour change starts with changing biology
Willpower programs fail because they argue with physiology. Fix the signal first and the behaviour follows.
The through-line
Four systems we keep coming back to.
Across every issue, the same four systems decide how fast a person's half-life runs down. They are also the four things precision biology can actually measure and move.
Genetics
Six genes, read as risk you can act on rather than fate.
The gut microbiome
The body's detox organ, and the first system a modern diet breaks.
Metabolic signal
Glucose and insulin as the earliest readable warning of decay.
Behaviour
Change the biology and the behaviour stops being a willpower problem.
Ranjan Sinha
Half-Life:100
Four fires, and how to put them out early.
Cover concept, not final art.
The book
Writing in progressFour fires that erode health.
Ranjan Sinha, Digbi Health's CEO, is writing the long-form argument behind Half-Life:100. Each chapter takes one fire and starts at the root cause, diagnosing why it started, rather than opening with a lab panel or a symptom list.
The promise is better health and a fuller life, written to be read by anyone, not gatekept as a premium or academic text.
The metabolic fire
Insulin, glucose and fat storage, traced back to why the system tipped in the first place.
The inflammatory fire
Gut, immune signalling and the low-grade burn that shortens a life quietly.
Cancer
Risk read through biology and environment rather than through a screening schedule.
The aging brain
Alzheimer's and cognitive decline, and how early the groundwork is laid.
"I kept meeting people who had done everything they were told to do and were still getting sicker. The tests were fine. The explanation was missing. This book is the explanation."
Targeted for April 14–15, 2027. Timeline not locked.